Saturday, February 28, 2009
A little stress may keep cells youthful
Do you know that a lot of stress can turn your hair gray, but a little stress can actually delay aging. A protein tied to protecting cells from stress also helps slow aging.
Exposure to heat, cold or heavy metals can damage proteins and unravel them from their usual conformations — trauma that can cause cell death.
But cells have a damage-limiting mechanism called the heat shock response to combat these and other stresses. As part of the heat shock response, special protein repair molecules patch up the damaged proteins and refold them correctly, preventing death and extending the life of the cell.
Scientist have found out about something new: Sirtuin 1, or SIRT1, an aging-related protein. It’s the first evidence linking SIRT1 to the protein-protecting heat shock response. Scientist have found out too that that Sirtuin 1 has many roles in longevity. It’s remarkable that it also affects heat shock response.”
One mild stress that can activate the heat-shock response is a calorie-restricted diet, which has been shown to extend the life of all species tested so far, including mice and dogs. Calorie-restricted diets increase the levels of Sirtuin 1, or SIRT1, an aging-related protein.
When a cell is under stress, heat shock factor 1 latches on to DNA and steps up production of the protein repair molecules. But the cell can’t exist in a state of emergency all the time. After the protein repair molecules become abundant, the damage-limiting mechanism shuts itself down
I have learnt that with this i should introduce some stress to myself so maybe i won't age at all. i have learnt so many things about our selves and how cells work( Done by: Nicholas) ¶ 7:28 PM
Do you know that a lot of stress can turn your hair gray, but a little stress can actually delay aging. A protein tied to protecting cells from stress also helps slow aging.
Exposure to heat, cold or heavy metals can damage proteins and unravel them from their usual conformations — trauma that can cause cell death.
But cells have a damage-limiting mechanism called the heat shock response to combat these and other stresses. As part of the heat shock response, special protein repair molecules patch up the damaged proteins and refold them correctly, preventing death and extending the life of the cell.
Scientist have found out about something new: Sirtuin 1, or SIRT1, an aging-related protein. It’s the first evidence linking SIRT1 to the protein-protecting heat shock response. Scientist have found out too that that Sirtuin 1 has many roles in longevity. It’s remarkable that it also affects heat shock response.”
One mild stress that can activate the heat-shock response is a calorie-restricted diet, which has been shown to extend the life of all species tested so far, including mice and dogs. Calorie-restricted diets increase the levels of Sirtuin 1, or SIRT1, an aging-related protein.
When a cell is under stress, heat shock factor 1 latches on to DNA and steps up production of the protein repair molecules. But the cell can’t exist in a state of emergency all the time. After the protein repair molecules become abundant, the damage-limiting mechanism shuts itself down
I have learnt that with this i should introduce some stress to myself so maybe i won't age at all. i have learnt so many things about our selves and how cells work( Done by: Nicholas) ¶ 7:28 PM
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